Can nitrofurantoin be used to treat kidney infections and what are the limitations of its use in upper urinary tract infections compared to other antibiotics?
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Can nitrofurantoin be used to treat kidney infections and what are the limitations of its use in upper urinary tract infections compared to other antibiotics?
Nitrofurantoin is primarily used for lower UTIs and is less effective for kidney infections due to inadequate tissue concentrations.
Nitrofurantoin is not recommended for upper UTIs like pyelonephritis, as it does not reach therapeutic levels in kidney tissues.