What is the risk of developing lactic acidosis while taking Metformin and what symptoms or conditions increase this likelihood?
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What is the risk of developing lactic acidosis while taking Metformin and what symptoms or conditions increase this likelihood?
The risk of lactic acidosis from metformin is low, about 3 per 100,000. Risk factors include kidney disease, excessive alcohol use, and severe dehydration. Symptoms include weakness, trouble breathing, and sudden change in bowel habits.
1. The risk of lactic acidosis from metformin is low but rises with conditions like kidney failure, liver disease, and severe dehydration.
2. Lactic acidosis from metformin is rare but can increase with kidney impairment, alcohol misuse, or if used with other diabetes drugs.
3. Metformin rarely causes lactic acidosis; risk factors include renal disease, excessive alcohol intake, and acute heart failure.
4. While uncommon, metformin-related lactic acidosis risk increases in the presence of renal insufficiency, hepatic disease, or alcohol abuse.