Can Metformin be used in managing certain cancers? What evidence supports its anti-tumor properties, particularly in cancers linked to metabolic dysfunction?
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Metformin has shown promise in oncology, particularly in reducing the incidence and improving survival of cancers like breast and colorectal cancer, possibly due to its effects on metabolic dysfunction.
Evidence suggests metformin may inhibit tumor growth in metabolic-related cancers, such as endometrial and liver cancer, by affecting cellular metabolism and reducing insulin resistance.