Can prolonged Glimepiride therapy contribute to beta-cell burnout and what measures can be taken to prevent this potential complication?
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Can prolonged Glimepiride therapy contribute to beta-cell burnout and what measures can be taken to prevent this potential complication?
Prolonged use of Glimepiride can potentially lead to beta-cell burnout by overstimulating insulin production. To prevent this, regular monitoring of beta-cell function and combining Glimepiride with metformin or GLP-1 agonists can be effective.