Can ciprofloxacin be safely used in patients with genetic mutations affecting drug metabolism, such as CYP450 polymorphisms and how do these genetic variations affect its efficacy or safety?
Lakshya KumarExplorer
Can ciprofloxacin be safely used in patients with genetic mutations affecting drug metabolism, such as CYP450 polymorphisms?
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Ciprofloxacin is not significantly metabolized by CYP450 enzymes; therefore, CYP450 genetic variations generally do not affect its safety or efficacy.