Are there instances where Metformin use leads to localized swelling in the hands or feet and what underlying mechanisms might cause this reaction?
Gaurav ChauhanContributor
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Metformin is not typically linked to localized swelling in hands or feet, known as peripheral edema. This symptom is more commonly associated with medications like calcium channel blockers.
Metformin can occasionally cause swelling in hands or feet, potentially due to fluid retention. This might result from kidney function changes affecting fluid balance.