How does assisted hatching enhance the success of IVF, and in which cases is this technique most commonly applied?
Gaurav ChauhanContributor
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Assisted hatching is a technique used during in vitro fertilization (IVF) to enhance the success rate of embryo implantation by helping embryos to hatch out of their outer layer, known as the zona pellucida. This technique involves making a small hole or thinning a part of zona pellucida, which can make it easier for the embryo to implant into the uterine lining.
Assisted hatching is most commonly applied in the following cases:
1. Advanced Maternal Age: Women over the age of 35 may have harder zona pellucida, which could make it more challenging for embryos to hatch naturally.
2. Poor Embryo Quality: If the embryo has a thicker or tougher zona pellucida, it may benefit from assisted hatching to increase the chances of successful implantation.
3. Previous IVF Failure: In cases where previous IVF cycles have not been successful, assisted hatching may be considered to improve the chances of implantation.
4. Frozen Embryo Transfer (FET): Some embryos that have been frozen and thawed may benefit from assisted hatching to improve their chances of successful implantation.
5. Diminished Ovarian Reserve: Women with diminished ovarian reserve may also benefit from assisted hatching to increase the chances of successful implantation.
It is essential to note that assisted hatching should only be recommended after a thorough evaluation by a fertility specialist, as it may not be suitable
Assisted hatching improves IVF success by thinning the embryo’s shell, aiding implantation. It’s mainly used for older women, those with thick zona pellucida, or previous IVF failures.