What are the potential hepatic effects of Diphenhydramine, and is it safe for use in patients with preexisting liver conditions or impairments?
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What are the potential hepatic effects of Diphenhydramine, and is it safe for use in patients with preexisting liver conditions or impairments?
Diphenhydramine can be hepatotoxic, causing liver enzyme elevations. Use caution in patients with liver disease; lower doses may be necessary.
Diphenhydramine may exacerbate liver conditions by increasing enzyme levels. It should be used carefully under medical supervision in patients with hepatic impairment.