Preimplantation genetic testing (PGT) is a technique used during in vitro fertilization (IVF) to improve the chances of a successful pregnancy and reduce the risk of passing genetic disorders or abnormalities to the offspring. PGT involves testing embryos for specific genetic conditions before they are implanted in the uterus.

1. Improved IVF Outcomes:

– PGT helps identify embryos that are chromosomally normal, reducing the chances of miscarriage and increasing the likelihood of a successful pregnancy.

– By selecting genetically healthy embryos for transfer, PGT can improve implantation rates and reduce the risk of multiple pregnancies (e.g., twins or triplets) often associated with IVF.

2. Specific Conditions or Abnormalities Detected:

– PGT can detect numerical chromosomal abnormalities, such as Down syndrome (trisomy 21), Turner syndrome, Klinefelter syndrome, and other aneuploidies.

– It can identify specific genetic disorders carried by the parents, such as cystic fibrosis, Huntington’s disease, Duchenne muscular dystrophy, or sickle cell anemia.

– PGT can also detect chromosomal translocations or deletions that may lead to recurrent miscarriages or infertility issues.

By identifying embryos free of specific genetic conditions or abnormalities, PGT helps select the healthiest embryos for transfer, thereby increasing the chances of a successful pregnancy and reducing the risk of passing on genetic disorders to the offspring.