How does Clonidine help reduce refractory hypertension? What mechanisms make it effective in patients who fail to respond to other antihypertensive treatments?
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How does Clonidine help reduce refractory hypertension? What mechanisms make it effective in patients who fail to respond to other antihypertensive treatments?
Clonidine reduces refractory hypertension by stimulating α2-adrenergic receptors in the brain, which decreases peripheral vascular resistance and heart rate, effectively lowering blood pressure.