What are the considerations for using leuprolide in transgender hormone therapy, and how does it support gender-affirming care for individuals undergoing transition?
What are the potential cognitive effects of leuprolide treatment, and how might hormonal changes contribute to issues such as memory loss or decreased concentration?
How does leuprolide therapy affect metabolic parameters, including glucose metabolism and lipid profiles, and what are the risks for developing metabolic syndrome during treatment?
What are the implications of leuprolide-induced hypoestrogenism in women, and how does it affect symptoms such as vasomotor instability or bone health?
How does leuprolide interact with other medications commonly prescribed in oncology, and what precautions are necessary to avoid adverse drug interactions?
What are the key challenges and considerations in administering leuprolide for metastatic prostate cancer, and how can these challenges be addressed to improve patient outcomes?
How does leuprolide influence bone mineral density over extended treatment periods, and what preventive measures can be taken to minimize the risk of osteoporosis?