How does Diphenhydramine differ from other first-generation antihistamines like Chlorpheniramine or Hydroxyzine in terms of sedation and duration of action?
Sahil KapoorExplorer
How does Diphenhydramine differ from other first-generation antihistamines?
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Diphenhydramine causes more sedation than Chlorpheniramine and has a similar sedative effect as Hydroxyzine. Its effects last 4-6 hours.