How does Losartan interact with diuretics like hydrochlorothiazide, and what benefits or risks arise when combining these medications for the treatment of hypertension or fluid retention?
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Losartan and hydrochlorothiazide work synergistically to lower blood pressure. Losartan dilates blood vessels, while hydrochlorothiazide reduces fluid volume, enhancing antihypertensive effects but possibly increasing dehydration risk.