How does penicillin affect the absorption of other medications, potentially reducing their effectiveness or causing side effects and what measures can ensure safe and effective co-administration?
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How does penicillin affect the absorption of other medications, potentially reducing their effectiveness or causing side effects and what measures can ensure safe and effective co-administration?
1. Penicillin can decrease the absorption of some drugs by altering gut flora or pH, potentially reducing their effectiveness.
2. To safely co-administer medications with penicillin, monitoring therapeutic levels and adjusting doses as needed is crucial.
3. Some drugs may become less effective when taken with penicillin due to interference with gastrointestinal absorption; closely monitor patient response.
4. When penicillin is used with other medications, adjusting the timing of administration can prevent reduced absorption and maintain efficacy.